DERMAPEN ™, thanks to the pulsating needles that facilitate the delivery of active substances in the epidermis and dermis, provides unparalleled stimulation of fibroblasts. Microtrauma causes the skin to use the body’s natural ability and innate ability to repair the skin through the physiological induction of collagen.
Controlled precision DERMAPEN ™ allows the identification of the three phases of its mechanism of action in the process of skin cells and stimulates the recovery of its structure.
- to stimulate the production of collagen, elastin and hyaluronic acid
- Stimulation of fibroblasts by treatment with platelet-derived growth factor
- to improve the density and elasticity
- improvement in skin nourishment
The first stage begins with the secretion of platelet-derived growth factors. It cascades the creation of new skin cells, chemotaxis of fibroblasts, stimulation of fibroblast proliferation and extracellular matrix production.
The processes of proliferation of skin cells cause further release of growth factors with fibroblasts, keratinocytes and monocytes leading to the second skin remodelling phase, in which the formed collagen type III, IV and I, elastin, proteoglycans, GAG and are stimulated angiogenesis.
